Avoid like the plague

Generated image of a woman and child avoiding a sick man
To avoid like the plague means to put effort into staying as far away as possible from something you don't want to deal with.

The phrase comes from the historical fear of the plague, a deadly disease that spread rapidly and caused widespread death. Because people tried desperately to avoid it, the expression became a way to describe extreme avoidance.

He avoids spicy food like the plague.